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For biopharma industry

The era of precision oncology is empowering the biopharmaceutical industry to deliver breakthrough therapeutics for patients with cancer.

Precision medicine is driving a new
era in oncology drug development

Biopharma companies are at the forefront of introducing new targeted therapies that have redefined the management of advanced cancer. These treatments target the specific genomic alterations or biomarkers of a patient, which can significantly extend progression-free survival compared to traditional chemotherapy or immunotherapy.1-7 And the number of therapies keeps growing. Furthermore, advances in testing, including faster and less invasive blood testing, are supporting development of these new therapies, including by accelerating patient enrollment in clinical trials, which is a common challenge.8

Helping pharmaceutical companies accelerate precision oncology drug development

As innovative research and development continues, liquid biopsy tests are also helping biopharmaceutical companies learn more about cancer, by revealing tumor evolution and resistance in response to interventional therapies. Robust clinical-genomic datasets are increasingly deepening the understanding of cancer, offering companies real-world insights into anti-cancer therapies.

Precision oncology is an essential part of the future of cancer care, which may one day even include targeted interventional therapies to help prevent disease progression at earlier stages.

See our complete Biopharma Solutions product offering here. Contact us below to learn more about whether Guardant Health is the right partner for your precision oncology drug development.

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Contact our biopharma team to see how we can help you accelerate precision oncology and bring the next generation of cancer therapies to patients sooner.

  1. Shaw AT, Riely GJ, Bang Y-J, et al. Crizotinib in ROS1-rearranged advanced non-small-cell lung cancer (NSCLC): updated results, including overall survival, from PROFILE 1001. Annals of Oncology. 2019;30(7):1121-1126.
  2. Ramalingam SS, Gray JE, Ohe Y, et al. Osimertinib vs comparator EGFR-TKI as first-line treatment for EGFRm advanced NSCLC (FLAURA): Final overall survival analysis. Annals of Oncology 2019;30(5):v851-v934.
  3. Garon EB, Hellmann MD, Costa EC, et al. Five-year long-term overall survival for patients with advanced NSCLC treated with pembrolizumab: Results from KEYNOTE-001. J Clin Oncol. 2019;37(28):2518-2527.
  4. Camidge DR, Dziadziuszko R, Peters S, et al. Updated Efficacy and Safety Data and Impact of the EML4-ALK Fusion Variant on the Efficacy of Alectinib in Untreated ALKPositive Advanced Non–Small Cell Lung Cancer in the Global Phase III ALEX Study. J Thorac Oncol. 2019;14(7):1233-1243.
  5. https://www.hcp.novartis.com/products/tafinlar-mekinist/metastatic-nsclc/efficacy/ Accessed online Jan. 10, 2020.
  6. Gadgeel SM, Garassino MC, Esteban E, et al. KEYNOTE-189: Updated OS and progression after the next line of therapy (PFS2) with pembrolizumab (pembro) plus chemo with pemetrexed and platinum vs placebo plus chemo for metastatic nonsquamous NSCLC. J Clin Oncol. 2019;37(suppl; abstr 9013).
  7. Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med. 2006;14;355(24):2542-2550.
  8. Nakamura, Y., Taniguchi, H., Ikeda, M. et al. Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies. Nat Medicine (2020).